Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
gga-mir-30b: The gga-mir-30b is a member of the gga-miR-30 family, which consists of five members, including gga-miR-30a, gga-mir-30b, gga-miR-30c, gga-miR-30d, and gga-miR-30e. These members share a seed sequence but differ at their 3' ends, allowing for a slightly different repertoire of targets [PMC7936154]. Previous studies have shown that gga-mir-30b is differentially expressed in various contexts. For example, it is differentially expressed in chicken lungs infected with avian influenza virus [PMC7936154]. Additionally, it is differentially expressed in A549 cells infected with swine-origin H1N1 or avian-origin H7N7 influenza A virus [PMC7936154]. In mice infected with recombinant influenza A H1N1 virus strains or highly pathogenic H5N1 avian virus in cynomolgus macaques, the expression of gga-mir-30b was also altered [PMC7936154]. Furthermore, it has been shown that gga-mir-30b targets the M and NA genes of avian influenza virus [PMC3496578]. In chicken lung and trachea infected with avian influenza virus, the expression of several miRNAs including gga-mir-30b was found to be differentially regulated [PMC5389138]. Finally, in RSS chicken samples four up-regulated miRNAs (gga-miR-221, gga-mir-30b,g ga-miR- 3c and ga -miR -215) and one down-regulated miRNA (g ga -mi R -375) were validated using RT-qPCR [PMC4444097].
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset