Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
rno-mir-30b: Rno-mir-30b is a microRNA that is processed into two mature forms, rno-mir-30b-3p and rno-mir-30b-5p, and their targets were combined for further analysis [PMC2990713]. The same was done for rno-mir-30d, where the targets of rno-miR-30d and rno-miR-30d* were merged [PMC2990713]. Rno-mir-30b has 1868 targets, while rno-mir-30d has 1776 targets [PMC2990713]. Rno-mir-30b and rno-mir-30d are both covered by a "gain" region on chromosome 7 within a region of only 3.8 Kb [PMC2990713]. These microRNA genes are part of a set of T2D-associated CNV regions that include several novel T2D susceptibility loci involving protein-coding genes and two microRNA genes [PMC2990713] [PMC4631338]. Rno-mir-30b overexpression has been shown to have an anti-apoptotic effect on cardiomyocytes during the early phase of myocardial IR injury in a rat model [PMC7238603]. Only five dysregulated miRNAs, including rno-miR183/96, rno-miR-150, and rno-miR206, were observed in two or more studies, suggesting that various factors can influence miRNA expression in different contexts [PMC10045079].
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset