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Homo sapiens (human) microRNA hsa-mir-130b precursor secondary structure diagram

Homo sapiens (human) microRNA hsa-mir-130b precursor URS000075E379_9606

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MIR130B: Importantly, recent studies have documented, while responding to an H. pylori infection, the infiltration of a unique subset of PMN-MDSCs which express MIR130B, an endogenous short noncoding RNA, as well as TNF-α, known to contribute to immunotherapy-resistant gastric cancer [PMC8699100]. Cyld was recently shown to be a bona fide target of MIR130B and that the NFκb subunit p65 was a potential regulator of the MIR130B locus [PMC7377952]. Therefore, we determined whether there is a feedback loop between NFκb activation and MIR130B expression, by using the human myeloid HL-60 cell line [PMC7377952].

Genome locations

Gene Ontology annotations


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2D structure Publications