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Homo sapiens (human) microRNA hsa-mir-19b precursor (hsa-mir-19b-1) URS00003BACA4_9606

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MIR19B1: MIR19B1 is a member of the miR-17~92 cluster and has been associated with various conditions and diseases. It has been linked to the presence of right renal agenesis [PMC9090243]. Additionally, MIR19B1, along with MIR17, MIR18A, and MIR20A, is part of the miR-17–92 cluster on chromosome 13 that is upregulated in lung cancer cell lines and involved in repression of proliferation inhibition and apoptotic agents [PMC6418160]. In the context of malignancy, MIR19B1 has been found to be one of the most upregulated miRNAs [PMC9390975]. In individuals with non-syndromic CAKUT (congenital anomalies of the kidney and urinary tract), pathogenic variants in MIR19B1 have been identified [PMC7998154]. The miR-17~92 cluster genes, including MIR19B1, have been found to be encompassed by a microduplication at 13q31.3 [PMC4005632]. The host gene for the miR-17~92 cluster is MIR17HG, which encodes for six individual miRNAs including MIR19B1 [PMC4005632]. Copy gains or amplifications affecting this locus have also been found to impact the miR17-92 cluster genes [PMC9259584]. References: [PMC9090243] - [PMC6418160] - [PMC9390975] - [PMC7998154] - [PMC4005632] - [PMC9259584] -

Genome locations

Gene Ontology annotations


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This sequence is found in 52 other species

  1. Aotus nancymaae (Ma's night monkey) microRNA 19b-1 (ENSANAG00000013287.1)
  2. Ateles geoffroyi microRNA age-mir-19b precursor (age-mir-19b-1)
  3. Bos taurus (cattle) microRNA bta-mir-19b precursor
  4. Camelus dromedarius (Arabian camel) microRNA 19b-1 (ENSCDRG00005012588.1)
  5. Capra hircus (goat) microRNA chi-mir-19b precursor
  6. Carlito syrichta microRNA 19b-1 (ENSTSYG00000022738.2)
  7. Catagonus wagneri (Chacoan peccary) microRNA 19b-1 (ENSCWAG00000004675.1)
  8. Cebus imitator microRNA 19b-1 (ENSCCAG00000013566.1)
  9. Cercocebus atys microRNA 19b-1 (ENSCATG00000021901.1)
  10. Cervus elaphus hippelaphus ncRNA
  11. Chlorocebus sabaeus microRNA 19b-1 (ENSCSAG00000026697.1)
  12. Choloepus hoffmanni miRNA (ENSCHOG00000014732.1)
  13. Colobus angolensis palliatus miRNA (ENSCANG00000008268.1)
  14. Dasypus novemcinctus (nine-banded armadillo) microRNA 19b-1 (ENSDNOG00000027362.1)
  15. Dipodomys ordii (Ord's kangaroo rat) microRNA 19b-1 (ENSDORG00000027454.1)
  16. Erinaceus europaeus miRNA (ENSEEUG00000016139.1)
  17. Gorilla gorilla gorilla ggo-mir-19b-1 (ENSGGOG00000034672.2)
  18. Gorilla gorilla microRNA ggo-mir-19b precursor (ggo-mir-19b-1)
  19. Heterocephalus glaber microRNA 19b-1 (ENSHGLG00000022122.1, ENSHGLG00100022781.1)
  20. Ictidomys tridecemlineatus microRNA 19b-1 (ENSSTOG00000016662.1)
  21. Lagothrix lagotricha microRNA lla-mir-19b precursor (lla-mir-19b-1)
  22. Loxodonta africana (African savanna elephant) microRNA 19b-1 (ENSLAFG00000024970.1)
  23. Macaca mulatta microRNA mml-mir-19b precursor (mml-mir-19b-1)
  24. Macaca nemestrina (pig-tailed macaque) microRNA mne-mir-19b precursor (mne-mir-19b-1)
  25. Mandrillus leucophaeus (Drill) microRNA 19b-1 (ENSMLEG00000014182.1)
  26. Microcebus murinus (gray mouse lemur) microRNA 19b-1 (ENSMICG00000018257.3)
  27. Mustela putorius furo (Domestic ferret) microRNA 19b-1 (ENSMPUG00000022943.1)
  28. Myotis lucifugus (little brown bat) microRNA 19b-1 (ENSMLUG00000029659.1)
  29. Otolemur garnettii microRNA 19b-1 (ENSOGAG00000017419.1)
  30. Ovis aries microRNA oar-mir-19b precursor
  31. Pan paniscus microRNA ppa-mir-19b precursor (ppa-mir-19b-1)
  32. Pan troglodytes (chimpanzee) microRNA ptr-mir-19b precursor (ptr-mir-19b-1)
  33. Pongo abelii (Sumatran orangutan) miRNA
  34. Pongo pygmaeus (Bornean orangutan) microRNA ppy-mir-19b precursor (ppy-mir-19b-1)
  35. Propithecus coquereli (Coquerel's sifaka) microRNA 19b-1 (ENSPCOG00000002195.1)
  36. Pteropus vampyrus microRNA 19b-1 (ENSPVAG00000024416.1)
  37. Rhinopithecus bieti microRNA 19b-1 (ENSRBIG00000005895.1)
  38. Rhinopithecus roxellana microRNA 19b-1 (ENSRROG00000006323.1)
  39. Saguinus labiatus microRNA sla-mir-19b precursor (sla-mir-19b-1)
  40. Saimiri boliviensis boliviensis microRNA 19b-1 (ENSSBOG00000019788.1)
  41. Tursiops truncatus (bottlenosed dolphin) microRNA 19b-1 (ENSTTRG00000023415.1)