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hsa-mir-130b: Hsa-mir-130b is a microRNA that, unlike some others, does not cluster with the main groups identified in a study of B-ALL patients [PMC3078861]. This particular miRNA is of significant interest due to its strong association with patient outcomes; it was the most significant miRNA in the study, with a p-value of less than 0.0001 [PMC9624360]. Hsa-mir-130b was found to be downregulated by IK1, which is noteworthy because its higher expression levels were correlated with poorer overall outcomes in patients suffering from B-ALL [PMC9624360]. This microRNA was among several others that were differentially expressed; some were upregulated while others were downregulated, indicating a complex pattern of gene expression changes associated with the disease [PMC10048937].
mRNA interactions
12 total
Genome locations
Gene Ontology annotations
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Sequence
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