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Rattus norvegicus (Norway rat) rno-miR-221-3p URS0000170CF4_10116

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rno-mir-221: rno-mir-221 is a microRNA that has been quantified in various rat brain regions, including the prefrontal cortex (PFC), nucleus accumbens (NAc), and dorsal striatum, using quantitative PCR techniques [PMC4772274]. This microRNA is differentially expressed in rats with polycystic ovary syndrome (PCOS) compared to control rats, indicating a potential role in the pathophysiology of this condition [PMC4838149]. Additionally, rno-mir-221 is notably abundant in dihydrotestosterone (DHT)-treated ovaries, suggesting its involvement in ovarian responses to androgenic stimuli [PMC3682887]. It is also one of the microRNAs with experimentally validated targets according to ingenuity databases, which implies that rno-mir-221 may have multiple biological functions and could be involved in complex regulatory networks [PMC3682887]. Furthermore, rno-mir-221 has been associated with cardiac hypertrophy based on microRNA profiling studies, which could link it to cardiac pathologies [PMC5856749].

mRNA interactions total

Genome locations

Gene Ontology annotations

Sequence

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This sequence is found in 59 other species

  1. Alligator mississippiensis ami-miR-221-3p
  2. Anolis carolinensis (green anole) Aca-Mir-221-P2a_3p (mature (guide))
  3. Bos taurus (domestic cattle) Bta-Mir-221-P2a_3p (mature (guide))
  4. Callithrix jacchus (white-tufted-ear marmoset) Cja-Mir-221-P2a_3p (mature (guide))
  5. Callorhinchus milii (elephant shark) Cmi-Mir-221-P2a_3p* (star (passenger))
  6. Canis lupus familiaris (dog) Cfa-Mir-221-P2a_3p (mature (guide))
  7. Capra hircus miR-221
  8. Cavia porcellus cpo-miR-221-3p
  9. Cervus elaphus cel-miR-221
  10. Chrysemys picta bellii (western painted turtle) Cpi-Mir-221-P2a_3p* (star (passenger))
  11. Columba livia Cli-Mir-221-P2a_3p (mature (guide))
  12. Cricetulus griseus (Chinese hamster) cgr-miR-221-3p
  13. Danio rerio (zebrafish) dre-miR-221-3p
  14. Dasypus novemcinctus dno-miR-221-3p
  15. Daubentonia madagascariensis dma-miR-221
  16. Echinops telfairi (small Madagascar hedgehog) Ete-Mir-221-P2a_3p (mature (guide))
  17. Equus caballus eca-miR-221
  18. Gadus morhua (Atlantic cod) Gmo-Mir-221-P2a1_3p (mature (guide))
  19. Gallus gallus (chicken) gga-miR-221-3p
  20. Gekko japonicus Gja-Mir-221-P2a_3p (mature (guide))
  21. Gorilla gorilla gorilla ggo-miR-221 (MIR221)
  22. Gorilla gorilla ggo-miR-221
  23. Haplochromis burtoni abu-miR-221
  24. Homo sapiens hsa-miR-221-3p
  25. Latimeria chalumnae (coelacanth) Lch-Mir-221-P2a_3p (mature (guide))
  26. Lepisosteus oculatus (spotted gar) Loc-Mir-221-P2a_3p (mature (guide))
  27. Loxodonta africana (African savanna elephant) Laf-Mir-221-P2a_3p (mature (guide))
  28. Macaca mulatta (Rhesus monkey) mml-miR-221-3p
  29. Maylandia zebra mze-miR-221
  30. Microcebus murinus mmr-miR-221
  31. Monodelphis domestica (gray short-tailed opossum) mdo-miR-221-3p
  32. Monopterus albus (swamp eel) Mal-Mir-221-P2a1_3p (mature (guide))
  33. Mus musculus (house mouse) mmu-miR-221-3p
  34. Neolamprologus brichardi (lyretail cichlid) nbr-miR-221
  35. Nomascus leucogenys nle-miR-221
  36. Notamacropus eugenii (tammar wallaby) Neu-Mir-221-P2a_3p (mature (guide))
  37. Ophiophagus hannah oha-miR-221-3p
  38. Oreochromis niloticus oni-miR-221
  39. Ornithorhynchus anatinus (platypus) Oan-Mir-221-P2a_3p* (star (passenger))
  40. Oryctolagus cuniculus (rabbit) ocu-miR-221-3p
  41. Oryzias latipes ola-miR-221
  42. Otolemur garnettii (small-eared galago) oga-miR-221
  43. Ovis aries miscellaneous RNA
  44. Pan paniscus ppa-miR-221
  45. Pan troglodytes ptr-miR-221
  46. Papio hamadryas pha-miR-221
  47. Pongo abelii (Sumatran orangutan) Pab-Mir-221-P2a_3p (mature (co-guide))
  48. Pongo pygmaeus ppy-miR-221
  49. Pundamilia nyererei pny-miR-221
  50. Saimiri boliviensis boliviensis (Bolivian squirrel monkey) sbo-miR-221
  51. Sarcophilus harrisii (Tasmanian devil) Sha-Mir-221-P2a_3p (mature (guide))
  52. Scyliorhinus torazame (cloudy catshark) Sto-Mir-221-P2a_3p* (star (passenger))
  53. Sphenodon punctatus (tuatara) Spt-Mir-221-P2a_3p (mature (guide))
  54. Taeniopygia guttata (zebra finch) tgu-miR-221-3p
  55. Takifugu rubripes (torafugu) fru-miR-221
  56. Tetraodon nigroviridis tni-miR-221
  57. Tor tambroides (Thai mahseer) miR-221-3p
  58. Xenopus laevis (African clawed frog) Xla-Mir-221-P2a4_3p (mature (guide))
  59. Xenopus tropicalis xtr-miR-221
Relationships

Molecular Relationships

Publications