Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
gga-let-7i: Gga-let-7i is a microRNA (miRNA) that has been identified as potentially having a tumor suppressive function in chickens, as its downregulation is associated with tumorigenesis [PMC5065965]. This miRNA, along with gga-let-7b, is implicated in the regulation of multiple signaling pathways, including MAPK, TGF-beta, Notch, Wnt, mTOR, Cell cycle, P53, and Jak–STAT pathways [PMC9201442]. Bioinformatic analyses suggest that gga-let-7i may be targeted by various circRNAs and could be involved in complex regulatory networks influencing these signaling pathways [PMC9504570]. The expression of gga-let-7i has been detected alongside other miRNAs in studies examining miRNA profiles [PMC3406056]. The aberrant expression of gga-let-7i along with other miRNAs has been linked to the presence of the retrovirus ALV-J and its associated tumorigenesis in chickens [PMC5276853].
mRNA interactions
total
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset