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mmu-mir-135b: Mmu-mir-135b is a miRNA located on mouse chromosome 1, with a primary transcript length of approximately 15 kb and 5' and 3' ends located around 7-8 kb upstream and downstream of the miRNA [PMC2238936]. It is expressed on day 3 but not on day 5, unlike mmu-miR-21 and mmu-miR-291-3p which maintain the same targets from day 3 to day 5 [PMC9149258]. Mmu-mir-135b is one of the five miRNAs that participate in both early and late stages, along with mmu-mir-200a, mmu-mir-200b, mmu-mir-494, and mmu-mir-503 [PMC3866260]. It is associated with HOXA4 and two joint target genes [PMC7074395]. However, further investigation is needed for genes such as mmu-miR-342, mmu-miR-135a, mmu-miR-206, and mmu-miR144 in mouse thymus as their studies have not been reported yet [PMC7074395]. Mmu-mir-135b is associated with PBX1 and three other DEMs in addition to five joint target genes [PMC7074395]. It has been found to be increased in the ventral midbrain but not significantly [PMC3861205]. The mirBridge approach has shown that Mmu-mir135b regulates the transforming growth factor-beta (TGF-beta) signaling pathway [PMC4077261].
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