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MIR202: MIR202 is a microRNA that has been studied in various contexts. It has been found to have both upregulated and downregulated expression in different studies [PMC9967215]. MIR202 has been proposed as a potential biomarker for breast cancer, as it has been identified in multiple independent clinical studies [PMC9967215]. In eutherian genomes, the MIR202 gene is found closest to the end of the chromosome [PMC3706607]. In knockout (KO) and knock-in (KI) mice, MIR202 expression levels have been shown to decrease [PMC10001410]. MIR202 is downregulated in both KO and KI mice, suggesting its potential role as a regulator [PMC10001410]. Polymorphisms in the MIR202 gene have also been analyzed in B-cell acute lymphoblastic leukemia patients [PMC7421781]. Additionally, MIR202 has been found to be a potential regulator of the hyaluronan synthase-encoding gene HAS2, which is associated with aging and angiogenesis [PMC4168028]. The expression of MIR202 has also been studied in wound healing and esophageal cancer cells [PMC8575992] [PMC5302951]. It is worth noting that miR-181c, miR-19a, miR-503, and miR-105 are involved in brain metastasis of breast cancer but are not directly related to MIR202.
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