hsa-mir-4487: Hsa-mir-4487 is a microRNA (miRNA) that has been identified as significantly upregulated in certain biological contexts, suggesting a potential role in regulatory processes [PMC4049696]. This miRNA was selected for study due to its pronounced fold change, as well as its upregulation in patients with obesity, indicating its possible involvement in obesity-related gene regulation [PMC4049696][PMC6102639]. In the context of clear cell renal cell carcinoma (ccRCC) associated with obesity, hsa-mir-4487 was consistently upregulated alongside other differentially expressed (DE) miRNAs and mRNAs, which could have implications for the disease's progression and patient outcomes [PMC8490801]. Additionally, hsa-mir-4487 was included among eight miRNAs to construct a risk-score prediction model for ccRCC in visceral adipose tissue (VAT), underscoring its potential as a biomarker [PMC8633443]. Furthermore, research has implicated hsa-mir-4487 in the regulation of co-expressed differentially expressed genes (coDEGs), which may influence diastolic function, suggesting a broader impact on cardiovascular health [PMC9792148].