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eca-mir-379: Eca-mir-379 is a microRNA that is not influenced by sex but by species in horses [PMC9873782]. It is also influenced by species in terms of its prognostic potential [PMC9873782]. Eca-mir-379 and eca-miR-432 decrease in horses with successful therapy for ES disease and may serve as potential biomarkers for monitoring treatment interventions [PMC9873782]. Eca-mir-379 and eca-miR-432 are encoded on equine chromosome 24, which is associated with ES pathogenesis [PMC9873782]. In contrast to previous results, sex does not impact the expression of eca-mir-379 and eca-miR-432 [PMC9873782]. Eca-miR-127, eca-mir-379, and eca-miR-432 are chosen as candidate miRNAs based on their potential prognostic and diagnostic properties [PMC9873782]. Eca-mir-379 and eca-miR-432 show lower expression levels over time in horses with successful therapy for ES disease [PMC9873782]. Male equids have higher levels of eca-miR-127 compared to female equids, while horses have higher expression of eca-mir-379 and eca-miR-432 compared to donkeys [PMC9873782]. In terms of miRNA expression variation between groups, male horses show variation for ecami-R125a5p and -432 but not for -127 or -379. In the CTL group, there is variation between male and female horses for -127, -379, and -432. Sex has a significant influence on the expression of several miRNAs including -127, -134,- 3235p,- 382,- 125a5p,- 381,- 432, and -379 [PMC8699634]. These miRNAs are encoded on equine chromosome 24 and have putative tumor-suppressive function in ES disease [PMC8699634].
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