Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
bta-mir-328: Bta-mir-328 is a microRNA that has been studied in relation to various aspects of cattle biology. It has been found to have a low ndG value compared to other microRNAs such as bta-miR-223 and lncRNA XR_003033296.1 [PMC8578396]. Bta-mir-328 is evolutionarily close to other microRNAs such as bta-miR-149-5p and bta-miR-185 in cow and wild yak, but distantly related to bta-miR-24-3p and bta-miR-874 [PMC8578396]. It has been shown to bind to three genes involved in a specific pathway [PMC8578396]. Bta-mir-328, along with other microRNAs like bta-miR-24-3p, bta-miR223, and bta-miR185, has been associated with bovine immune response [PMC8578396]. In a study comparing different stages of cattle development, the expression of bta-mir328 was found to be down-regulated in the BS stage compared with the CO stage [PMC9608168]. Bta-mir328 was also found to regulate target genes involved in cell division and growth [PMC9608168]. In another study comparing healthy cows with at-risk cows, several miRNAs including bta-mir328 were downregulated in healthy cows [PMC10000098]. One study identified an intersection between a predicted MRE for bta-mir328 and an annotated 3' UTR variant in SFTPA1 gene [PMC6061482]. The role of btmir328 in cattle is not well-studied but its human homolog has been shown to play a role in innate immune defense against Haemophilus influenza through negative regulation of phagocytosis [PMC6061482]. In a study comparing different time points, bta-mir328 was found to have a high betweenness in the downregulated miRNA group [PMC9445238].
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset