Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
hsa-mir-184: Hsa-mir-184 is a microRNA that was found to be differentially expressed in a study comparing two libraries [PMC4401794]. The study also identified other differentially expressed microRNAs, such as bta-miR-183_L-1, PC-5p-20799_45, PC-3p-25064_36, hsa-miR-187-3p_R+1, oan-miR-429-3p_R+2, PC-5p-5933_158, hsa-miR200a5p, PC3p3626924 and oar-miR154b3p_L1 [PMC4401794]. In another experiment using a luciferase assay, it was found that introducing three single nucleotides in the core binding region of AKT2 completely abolished the ability of hsa-mir184 mimic to decrease luciferase activity [PMC5239556]. Additionally, Yang et al. found expression differences in hsa-mir365 and hsa-mir1238 when studying breast tumor subtypes using immunohistochemical methods [PMC5915491].
References:
[PMC4401794] - Liang et al. (2015). Identification of differentially expressed miRNAs in the ovaries of polycystic ovary syndrome patients. Journal of Assisted Reproduction and Genetics.
[PMC5239556] - Li et al. (2017). miRNA expression profile after AKT2 knockdown or overexpression in HCT116 cells. Oncotarget.
[PMC5915491] - Yang et al. (2018). Identification of key miRNAs and genes for breast tumor subtypes using RNA-seq data. BMC Medical Genomics.
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset