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Homo sapiens let-7f-1 stem-loop (hsa-let-7f-1) URS00004BFD1E_9606

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MIRLET7F1: MIRLET7F1 is a microRNA gene that is included in a custom gene panel designed for mutation profiling of pediatric cancers [PMC7341754]. The panel includes coding exons of 366 cancer-associated genes, untranslated regions and introns of 16 genes for detecting structural variations, and specific regions for detecting TERT rearrangement and promoter/enhancer mutation [PMC7341754]. In addition, the panel includes the promoter and enhancer regions of FGFR3 and MYC, as well as 11 microRNA genes including MIRLET7F1 [PMC7341754]. In a study, MIRLET7F1 was identified as one of the candidate target genes in pediatric cancers [PMC5791735]. MIRLET7F1 interacts with HNRNPM along with other miRNAs, protein coding genes, rRNAs, lncRNAs, and pseudogenes [PMC9730017]. The SNP rs10512230 is flanked by the PTPDC1 gene along with MIRLET7A1 (Let-7a-1), MIRLET7F1 (Let-7f-1), and MIRLET7D (Let-7d) genes [PMC6202974]. These microRNA genes including MIRLET7A1, MIRLET7F1, and MIRLET7D are involved in cancer and DNA damage response pathways [PMC6202974]. The custom gene panel used targeted capture technology to analyze various genomic regions including microRNA genes like MIRLET7F1 for copy number analysis in pediatric cancers [PMC7815088].

Genome locations

Gene Ontology annotations


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This sequence is found in 60 other species

  1. Aotus nancymaae (Ma's night monkey) miRNA (ENSANAG00000013330.1)
  2. Balaenoptera musculus microRNA let-7f-1 (ENSBMSG00010006243.1)
  3. Bos taurus let-7f-1 stem-loop (bta-let-7f-1)
  4. Callithrix jacchus let-7 microRNA precursor
  5. Camelus ferus let-7 microRNA precursor
  6. Canis lupus familiaris let-7 microRNA precursor
  7. Capra hircus (Goat) microRNA let-7f (ENSCHIG00000009011.1)
  8. Carlito syrichta miRNA (ENSTSYG00000021948.2)
  9. Cebus imitator (Panamanian white-faced capuchin) microRNA let-7f-1 (ENSCCAG00000016223.1)
  10. Cercocebus atys (Sooty mangabey) miRNA (ENSCATG00000016195.1)
  11. Chlorocebus sabaeus let-7 microRNA precursor
  12. Colobus angolensis palliatus (Angola colobus) miRNA (ENSCANG00000008705.1)
  13. Cricetulus griseus (Chinese hamster) let-7 microRNA precursor
  14. Delphinapterus leucas (beluga whale) microRNA let-7f-1 (ENSDLEG00000009233.1)
  15. Dipodomys ordii (Ord's kangaroo rat) let-7 microRNA precursor
  16. Felis catus (domestic cat) let-7 microRNA precursor
  17. Fukomys damarensis (Damara mole-rat) let-7 microRNA precursor
  18. Gorilla gorilla gorilla (Western Lowland Gorilla) microRNA let-7f-1 (ENSGGOG00000032887.2)
  19. Gorilla gorilla (western gorilla) precursor microRNA let-7f-1
  20. Lagothrix lagotricha (brown woolly monkey) precursor microRNA let-7f-1
  21. Lemur catta (Ring-tailed lemur) precursor microRNA let-7f-1
  22. Macaca mulatta let-7f-1 stem-loop (mml-let-7f-1)
  23. Macaca nemestrina miRNA (ENSMNEG00000002240.1)
  24. Mandrillus leucophaeus miRNA (ENSMLEG00000013151.1)
  25. Marmota monax non-coding RNA
  26. Meriones unguiculatus miRNA (ENSMUGG00000014781.1)
  27. Mesocricetus auratus (golden hamster) let-7 microRNA precursor
  28. Microcebus murinus microRNA let-7f-1 (ENSMICG00000018146.3)
  29. Monodelphis domestica let-7f-1 stem-loop (mdo-let-7f-1)
  30. Monodon monoceros (narwhal) microRNA let-7f-1 (ENSMMNG00015013892.1)
  31. Mustela putorius furo miRNA (ENSMPUG00000020641.1)
  32. Neogale vison miRNA (ENSNVIG00000014765.1)
  33. Nomascus leucogenys microRNA let-7f-1 (ENSNLEG00000022324.2)
  34. Notamacropus eugenii microRNA let-7f-1 (ENSMEUG00000017286.1)
  35. Ochotona princeps (American pika) miRNA (ENSOPRG00000017439.1, ENSOPRG00000018731.1)
  36. Oryctolagus cuniculus (rabbit) let-7 microRNA precursor
  37. Otolemur garnettii miRNA (ENSOGAG00000017294.1)
  38. Ovis aries let-7 microRNA precursor
  39. Pan paniscus (bonobo) microRNA let-7f-1 (ENSPPAG00000007666.1)
  40. Panthera pardus (leopard) microRNA let-7f-1 (ENSPPRG00000014667.1)
  41. Panthera tigris altaica miRNA (ENSPTIG00000001463.1)
  42. Pan troglodytes ptr-let-7f-1 (ENSPTRG00000027785.3)
  43. Papio anubis (Olive baboon) let-7 microRNA precursor
  44. Phocoena sinus microRNA let-7f-1 (ENSPSNG00000003601.1)
  45. Physeter catodon microRNA let-7f-1 (ENSPCTG00005009367.1)
  46. Pongo abelii let-7 microRNA precursor
  47. Pongo pygmaeus let-7f-1 stem-loop (ppy-let-7f-1)
  48. Propithecus coquereli (Coquerel's sifaka) miRNA (ENSPCOG00000008326.1)
  49. Pteropus alecto let-7 microRNA precursor
  50. Pteropus vampyrus (large flying fox) miRNA (ENSPVAG00000027657.1)
  51. Rhinopithecus bieti miRNA (ENSRBIG00000008268.1)
  52. Rhinopithecus roxellana (Golden snub-nosed monkey) miRNA (ENSRROG00000002770.1)
  53. Saguinus labiatus (red-chested mustached tamarin) precursor microRNA let-7f-1
  54. Saimiri boliviensis boliviensis miRNA (ENSSBOG00000018655.1)
  55. Sarcophilus harrisii microRNA let-7f-1 (ENSSHAG00000019362.2)
  56. Ictidomys tridecemlineatus let-7 microRNA precursor
  57. Sus scrofa let-7 microRNA precursor
  58. Tupaia belangeri miRNA (ENSTBEG00000017944.1)
  59. Tupaia chinensis let-7 microRNA precursor
  60. Tursiops truncatus (bottlenosed dolphin) miRNA (ENSTTRG00000021522.1)