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ssc-mir-27a: Ssc-mir-27a is a type of microRNA that has been studied in various contexts. In a study on castrated male pigs, it was found that ssc-mir-27a was decreased in expression, along with ssc-miR-378, which is consistent with previous research showing that ssc-mir-27a negatively regulates adipocyte differentiation by inhibiting the expression of PPARγ [PMC3901342]. In intact male pigs, the expression levels of ssc-miR-21, ssc-miR-142-5p, ssc-mir-27a, ssc-miR-7134-3p and ssc-miR-103 were significantly higher compared to castrated male pigs [PMC3901342]. Long-term dietary resveratrol supplementation in pigs increased intramuscular fat content and upregulated the mRNA expression of PPARγ and other genes while downregulating the mRNA expression of CPT-1, SIRT1, and PPARα. This effect may be related to enhanced expression of ssc-miR-181a, ssc-miR-370, and reduced expression of ssc-mir-27a [PMC9921422]. Ssc-mir 27a was also found to be one of the most abundant miRNAs in liver samples [PMC6856533]. Additionally, it has been observed that miRNAs such as sccm mir 27a are associated with cell cycle regulation and apoptosis [PMC3968000]. Some small RNAs are generated from the loop or region between loop and stem structures in miRNAs such as let7e mir 27a and miRNA 30A [PMC4008308]. In a study on PRV infection in pigs it was found that mir 27A was upregulated while other miRNAs were downregulated [PMC4801506].
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