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mmu-mir-3474: mmu-mir-3474 is a microRNA that was found to be downregulated in response to high glucose (HG) stimulation in a study that identified specific alterations in microRNA expression [PMC7667287]. This particular microRNA has 378 potential target genes, indicating its potential involvement in a wide range of cellular processes [PMC7667287]. The downregulation of mmu-mir-3474 was consistent across different assessments, confirming its response to HG conditions [PMC7667287]. Additionally, mmu-mir-3474 is part of the mmu_circRNA_21040 related network, which includes 14 target miRNAs and 36 genes, suggesting its role in complex regulatory interactions [PMC9574125]. Furthermore, mmu-mir-3474 is also related to DARPP-32, a protein associated with dopaminergic neurotransmission and signal transduction pathways; this relationship was identified through the analysis of mouse-derived microRNAs using "TargetScanHuman" [PMC10132208]. The study utilized TaqMan MicroRNA Assays for accurate measurement and validation of miRNA expression levels including that of mmu-mir-3474 [PMC8007565].
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