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hsa-mir-513c: Hsa-mir-513c is a differentially expressed microRNA (DEmiRNA) that has been identified in various studies. In one study, the volcano plot and heat map analysis revealed hsa-mir-513c as one of the top 10 upregulated DEmiRNAs in MSC-released Exos [PMC9507792]. Another study found hsa-mir-513c to be significantly downregulated in metastatic samples [PMC7140886]. The downregulation of hsa-mir-513c has been shown to promote the proliferation and invasiveness of neuroblastoma and glioma cells [PMC7140886]. Interestingly, despite using the same source data, a panel of deregulated miRNAs showed no similarities with the set identified by another study, except for hsa-mir-513c [PMC7140886]. Hsa-mir-513c is part of a cluster on the human X chromosome that includes 15 miRNAs [PMC3563971]. It has also been found to be upregulated in HIV-1 infected cells [PMC4885076]. Additionally, hsa-mir-513c was among the top five most upregulated miRNAs in CAF-derived exosomes [PMC7581790]. In another analysis, hsa-mir-513c was among the significantly deregulated miRNAs detected in RB tumor samples and serum samples [PMC3547501].
References:
[PMC9507792]
[PMC7140886]
[PMC7140886]
[PMC3563971]
[PMC4885076]
[PMC7581790]
[PM3547501]
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Gene Ontology annotations
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