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hsa-mir-204: Hsa-mir-204 is a microRNA implicated in various cellular processes and diseases, including cancer. It has been observed to be downregulated in inflammatory breast cancer (IBC) patients, which is expected to result in increased levels of HMGA2, a transcriptional regulator [PMC4289319]. This microRNA also plays a role in clear cell renal cell carcinoma (ccRCC) development by potentially regulating the focal adhesion pathway [PMC7405617]. Furthermore, hsa-mir-204 downregulation has been associated with breast cancer susceptibility gene (BRCA) mutations and can be an indicator of overall survival in patients [PMC9918521]. In endometrial carcinoma cells, hsa-mir-204 has been shown to inhibit clonogenic growth, migration, and invasion through in vitro functional analyses [PMC4918724]. The assessment of hsa-mir-204 levels can be performed using TaqMan MicroRNA Assays [PMC4508825]. Additionally, hsa-mir-204 expression has been identified in various stages of intestinal type gastric cancer and is associated with specific tumor stages such as T4N1M0 [PMC4496000].
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